Skin Rash (Assessment & Diagnosis) — 34yo Woman | Dermatology | MCCQE1 Q#13442

MCCQE1 Question #13442

Dimension of Care

Chronic Care

Activity

Assessment & Diagnosis

Objective

Skin Rash

Section

Medicine / Family Medicine

Subject

Dermatology

Last updated: February 2026
A 34-year-old woman presents with recurrent, itchy wheals on her trunk and arms for 7 weeks. Individual lesions appear suddenly, migrate, and each resolves within 12 hours without bruising or skin breakdown. She sometimes has swelling of her lips and eyelids lasting up to 24 hours. She has no systemic symptoms, no new medications, and no history of hereditary angioedema. Examination shows several blanching, edematous wheals on the forearms without petechiae or purpura. Which clinical feature would be most concerning for an underlying systemic disease associated with chronic urticaria and should prompt targeted evaluation?
Full answer analysis and choices are available inside the practice session.